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Ralf J Ludwig Selected Research

Blister (Bulla)

2/2022Association between TH2 Cytokine Gene Polymorphisms and Risk of Bullous Pemphigoid.
12/2021Immunoglobulin M pemphigoid.
12/2021Granzyme B inhibition reduces disease severity in autoimmune blistering diseases.
1/2021More Severe Erosive Phenotype Despite Lower Circulating Autoantibody Levels in Dipeptidyl Peptidase-4 Inhibitor (DPP4i)-Associated Bullous Pemphigoid: A Retrospective Cohort Study.
12/2018Regulatory T-cell deficiency leads to pathogenic bullous pemphigoid antigen 230 autoantibody and autoimmune bullous disease.
1/2018Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2.
2/2017Clinical features and diagnosis of epidermolysis bullosa acquisita.
2/2017Reduced skin blistering in experimental epidermolysis bullosa acquisita after anti-TNF treatment.
1/2017The Leukotriene B4 and its Receptor BLT1 Act as Critical Drivers of Neutrophil Recruitment in Murine Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita.
1/2017Topically Applied Hsp90 Blocker 17AAG Inhibits Autoantibody-Mediated Blister-Inducing Cutaneous Inflammation.
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Ralf J Ludwig Research Topics

Disease

53Epidermolysis Bullosa Acquisita (Acquired Epidermolysis Bullosa)
10/2022 - 01/2011
35Bullous Pemphigoid (Pemphigoid)
02/2022 - 12/2010
33Inflammation (Inflammations)
01/2022 - 04/2002
30Autoimmune Diseases (Autoimmune Disease)
01/2021 - 04/2010
25Skin Diseases (Skin Disease)
10/2022 - 11/2002
23Blister (Bulla)
02/2022 - 08/2011
19Pemphigus (Pemphigus Vulgaris)
03/2022 - 09/2011
13Hypersensitivity (Allergy)
07/2017 - 12/2005
8Neoplasms (Cancer)
01/2022 - 04/2004
8Psoriasis (Pustulosis Palmaris et Plantaris)
01/2021 - 04/2002
8Thrombocytopenia (Thrombopenia)
07/2017 - 11/2006
5Vesiculobullous Skin Diseases (Subcorneal Pustular Dermatosis)
04/2015 - 04/2010
4Disease Progression
02/2017 - 02/2016
4Contact Dermatitis (Eczema, Contact)
03/2010 - 11/2005
3Infections
10/2022 - 12/2017
3Thrombosis (Thrombus)
07/2013 - 04/2007
3Neoplasm Metastasis (Metastasis)
08/2007 - 04/2004
2Hepatitis
10/2022 - 01/2021
2Alopecia Areata
01/2022 - 01/2020
2Acantholysis
01/2019 - 02/2012
2Atopic Dermatitis (Atopic Eczema)
01/2018 - 01/2018
2Hemorrhage
07/2013 - 11/2012
2Rheumatoid Arthritis
02/2013 - 09/2006
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2011 - 09/2006
2Wells syndrome
07/2005 - 05/2003
1Hepatitis B
10/2022
1Confusion (Bewilderment)
10/2022
1Epidermolysis Bullosa
01/2022
1IgA Vasculitis (Purpura, Schoenlein Henoch)
12/2021
1Asthma (Bronchial Asthma)
01/2021
1Eosinophilia
01/2021

Drug/Important Bio-Agent (IBA)

74AutoantibodiesIBA
10/2022 - 06/2010
39Collagen Type VIIIBA
10/2022 - 01/2011
18Immunoglobulin G (IgG)IBA
01/2022 - 02/2012
17AntibodiesIBA
10/2022 - 10/2009
12Heparin (Liquaemin)FDA LinkGeneric
07/2017 - 04/2004
11Proteins (Proteins, Gene)FDA Link
12/2021 - 11/2011
10AutoantigensIBA
01/2022 - 01/2012
9CytokinesIBA
02/2022 - 02/2013
8AntigensIBA
12/2021 - 01/2012
7Adrenal Cortex Hormones (Corticosteroids)IBA
01/2021 - 04/2010
7P-SelectinIBA
08/2010 - 03/2004
6AnticoagulantsIBA
07/2017 - 04/2004
5Fondaparinux (Arixtra)FDA Link
11/2015 - 12/2005
4Intravenous Immunoglobulins (IVIG)FDA Link
10/2022 - 04/2010
4Matrix Metalloproteinases (MMPs)IBA
01/2022 - 03/2013
4Therapeutic UsesIBA
01/2022 - 12/2017
4anti-type VII collagen autoantibodyIBA
01/2022 - 01/2017
4Peptides (Polypeptides)IBA
12/2021 - 06/2011
4Immunoglobulin A (IgA)IBA
12/2021 - 08/2014
4Complement System Proteins (Complement)IBA
12/2021 - 11/2011
4Immunoglobulin E (IgE)IBA
01/2021 - 11/2015
4Pharmaceutical PreparationsIBA
12/2020 - 11/2006
4Antigen-Antibody Complex (Immune Complex)IBA
12/2020 - 08/2014
4EpitopesIBA
01/2019 - 05/2015
4Biological ProductsIBA
01/2017 - 09/2005
3Rituximab (Mabthera)FDA Link
03/2022 - 09/2011
3Interleukin-10 (Interleukin 10)IBA
02/2022 - 08/2014
3Interleukin-6 (Interleukin 6)IBA
02/2022 - 02/2013
3DesmogleinsIBA
01/2021 - 01/2019
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 08/2014
3Collagen Type XVIIIBA
01/2018 - 08/2011
3Biomarkers (Surrogate Marker)IBA
12/2017 - 08/2010
3Nadroparin (Nadroparin Calcium)IBA
07/2017 - 12/2005
3Heat-Shock Proteins (Heat-Shock Protein)IBA
06/2015 - 01/2013
3DinitrofluorobenzeneIBA
03/2010 - 08/2006
2HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
01/2022 - 01/2021
2KalininIBA
01/2022 - 03/2013
2Desmoglein 3IBA
12/2021 - 02/2012
2Immunoglobulin M (IgM)IBA
12/2021 - 01/2020
2Immunosuppressive Agents (Immunosuppressants)IBA
01/2021 - 04/2010
2Chimeric Antigen ReceptorsIBA
01/2020 - 01/2017
2Dipeptidyl-Peptidase IV InhibitorsIBA
01/2020 - 01/2017
2Leukotriene B4IBA
01/2017 - 01/2017
2IntegrinsIBA
11/2015 - 11/2011
217- (dimethylaminoethylamino)- 17- demethoxygeldanamycinIBA
08/2014 - 06/2011
2Neutralizing AntibodiesIBA
04/2013 - 11/2005
2SelectinsIBA
04/2007 - 04/2002
2Enoxaparin (Lovenox)FDA LinkGeneric
03/2006 - 12/2005
1Hepatitis B Surface Antigens (HBsAg)FDA Link
10/2022
1Nucleic AcidsIBA
10/2022
1N-acetyltalosaminuronic acid (NAT)IBA
10/2022
1Interleukin-4 (Interleukin 4)IBA
02/2022
1Interleukin-5 (Interleukin 5)IBA
02/2022
1Interleukin-13IBA
02/2022
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2022
1Peptide Hydrolases (Proteases)FDA Link
01/2022
1CollagenIBA
01/2022
1Granzymes (Granzyme)IBA
12/2021
1Serine Proteases (Serine Protease)IBA
12/2021
1Imiquimod (Aldara)FDA LinkGeneric
01/2021
1Omalizumab (Xolair)FDA Link
01/2021
1Sitagliptin Phosphate (Januvia)FDA Link
01/2021
1Antihypertensive Agents (Antihypertensives)IBA
01/2021
1Local AnestheticsIBA
01/2021
1Phosphatidylinositols (Phosphatidylinositol)IBA
01/2021
1TGX 221IBA
01/2021
1VildagliptinIBA
01/2021

Therapy/Procedure

15Therapeutics
10/2022 - 11/2002
2Precision Medicine
01/2021 - 01/2020